Composite Outcome
an outcome measure in clinical research that combines two or more individual, clinically relevant events, domains, or endpoints into a single measure.
Outcome Measurement & Instrument Science
Terms focused on the development, evaluation, selection, and application of outcome measures and measurement instruments. This category includes domains, validity, reliability, feasibility, discrimination, measurement properties, composite outcomes, and instrument evaluation methodologies.
Clinimetric
the science and methodology of developing, evaluating, and applying clinical measurement tools (such as scales, indices, or composite measures) to quantify health status, symptoms, or functional outcomes in patients.
Clinician- Reported Outcome (ClinRO)
an outcome measure based on a clinician’s direct observation, clinical judgment, or examination findings of a patient’s health status.
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Clinical Outcome Assessment (COA)
a measure used to evaluate a patient’s health status or a clinical outcome.
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Candidate Domain
a health outcome domain identified as potentially important but not yet confirmed as part of a core set.
Broad Domain
a general or overarching category of related concepts that is typically too vague or wide-ranging to be measured directly.
Biological Marker
a measurable indicator of a biological state, process, or response to an exposure or intervention.