the systematic process of identifying, evaluating, and choosing the most appropriate tools or instruments to measure the agreed-upon core domains in a research study or clinical trial. This process ensures that the outcomes being measured are valid, reliable, and feasible within the study context.
Abbreviation: IS
Synonyms: Core Outcome Instrument Selection, Core Outcome Measurement Selection
Example
An OMERACT working group evaluating rheumatoid arthritis flare uses the instrument selection process to compare multiple pain assessment scales and selects the one with the strongest evidence of validity, reliability, and feasibility for inclusion in their core outcome set.