Synovial Tissue Biopsy in RCT Working Group

About

The Outcome Measures in Rheumatology (OMERACT) synovial tissue biopsy (STB) working group initiated an international effort to standardize STB analyses, define consensual items to inform treatment choices, and predict responses in rheumatoid arthritis (RA).
Six markers were identified for examination in a multicenter study designed to define an OMERACT-endorsed set of STB markers to predict responses to treatment.

 

Current Stage in the OMERACT Process

The group is standardizing biopsy markers that may help predict treatment response in RA. Consensus scoring and data analysis are nearing completion.

 

Latest Update

OMERACT 2025 Conference Highlights
Fellow Poster: Our OMERACT Fellow, Mario Ferraioli, presented a poster summarizing the current state of our work, sparking excellent conversations about next steps and collaborations.
👉 View the poster here
Lightning Talk: In a rapid-fire session, our team shared an upcoming teaser of the Special Interest Group (SIG) session taking place during the conference.
👉 Watch the lightning talk here
Closing Plenary Talk: We were also featured in the Closing Plenary, where we highlighted the activities of the (SIG).
👉 Watch the presentation here

Next Meeting

TBD

Meet the Team

aurelie.najm@gmail.com

Aurelie Najm, Ireland
Chair

Mihir Wechalekar

Mihir Wechalekar, Australia
Chair

VStrand linkedin_2278

Vibeke Strand, USA
Chair

mario ferraioli

Mario Ferraioli, Italy
Emerging Leader

Recent Publications

  1. Wechalekar, Mihir D., et al. “The 2018 OMERACT Synovial Tissue Biopsy Special Interest Group Report on Standardization of Synovial Biopsy Analysis.Journal of Rheumatology, vol. 46, no. 10, 2019, pp. 1365–68, https://doi.org/10.3899/jrheum.181062.

New to OMERACT?

OMERACT Working Groups follow a structured, consensus-driven approach to developing Core Outcome Sets. Explore how this process unfolds and discover more about how OMERACT advances outcome measurement in rheumatology.
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