About the Adult-onset Still's Disease Working Group

Adult-onset Still´s disease (AOSD) is a rare multisystem inflammatory disorder of unknown etiology, considered as a multigenic autoinflammatory syndrome. AOSD and systemic-onset juvenile idiopathic arthritis are considered a same disease continuum with different ages of onset. AOSD may present distinct clinical evolutions, from monophasic (monocyclic), intermittent to chronic pattern. The classic triad of symptoms is formed by high fever, evanescent rash, and arthritis or arthralgia, other commons manifestations may be present as sore throat, lymphadenopathy, hepatomegaly, serositis and elevated ferritin levels, erythrocyte sedimentation rate and C-reactive protein,  leukocytosis, normocytic normochromic anemia and thrombocytosis. Clinical and laboratory findings are not pathognomonic, the diagnosis should be of exclusion. Although uncommon, AOSD may present with serious complications such as macrophage activation syndrome. Currently, there is no universally accepted way of reporting outcomes in studies of this condition.

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Simone Appenzeller



Haner Direskeneli



Dan Furst


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Raouf Hajji



Umut Kalyoncu



Vani Abreu de Souza Filho



Emre Bilgin


Working Group Members:

Agnes Rauter
Ahmed Elsaman
Ahmed Seri Ibrahim Mohamed
Aleksander Lenert
Aya Akmal Amin
Bella Mehta
Blaise Bojo
Chu Hieu chi
Dan First
David Maher
Denise Bury
Elena Garcia Guijarro

Elise Dekker
Emre Bilgin
Esther Francisca Vicente-Rabaneda
Evelien Priem
Francesca Ingegnoli
Gary Choque
Gehad Maghraby
Ghaydaa Dabie
Gizem Sevik
Haner Direskeneli
Jan RenNkeck

Javier Rios
Jay Fiddler
Jean-Noel Talabardon
Joao Dias
Kapil Garg
Karen Natali Saravia Chocobar
Kayla Cadotte
Kyung Min Ko
Lays De Souza
Liliia Shvets
Madusha Menu Cristeen Jayasinghe

Maxine Isbel
Monica Vieth
Oliver Krâmer
Peter Tugwell
Raouf Hajji
Simone Appenzeller
Tamer Gheita
Teodora Serban
Tiffany Westrich-Robertson
Umut Kalyoncu
Vani Abreu de Souza Filho

Interested in joining the working group as a member?

We are excited to invite you to join the OMERACT mailing list! This will ensure you stay updated on our latest news and activities.
In addition to joining our mailing list, we also encourage you to become part of our active Working Groups. Being part of these groups is an opportunity to collaborate with experts in the field, contribute to important discussions, and influence the future direction of rheumatology outcomes research.
We look forward to your valuable contributions and active participation in our community.


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