Candidate Domain
A health outcome area identified as potentially important for a core outcome set, but not yet confirmed. It goes through a review and consensus process before being included.
Outcome Measurement & Instrument Science
Broad Domain
A wide, general category of health that is too vague to measure directly on its own. It serves as an umbrella for more specific, measurable areas called target domains. Not every specific area necessarily fits under a broad domain.
Biological Marker
A measurable sign in the body — such as a lab value or imaging finding — that indicates a biological state, disease, or response to treatment. Used to detect disease, track its progress, and guide treatment.
Technical Advisory Group
A standing group of methodological experts that provides independent guidance to OMERACT leadership and working groups, ensuring all initiatives follow rigorous and up-to-date methods.
Technical Advisory Group Read More »
Good Methods Checklist
An OMERACT tool for systematically assessing whether proper methodological standards have been followed in developing Core Outcome Sets and selecting measurement instruments.
Good Methods Checklist Read More »
Core Area
A broad category of health that must be addressed to fully evaluate an intervention. The four universally recognized OMERACT Core Areas are: Death/Lifespan, Life Impact, Pathophysiological Manifestations, and Societal/Resource Use.
Core Domain Set (CDS)
An agreed list of outcome domains considered essential to measure in all clinical trials for a specific condition. It defines what should be measured — not yet how. Developed through evidence review and stakeholder consensus.
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