Gout is the most common form of inflammatory arthritis and is caused by deposition of monosodium urate (MSU) crystals in and around joints, which provokes an intense inflammatory response. Gout manifests as episodes of intense joint pain, swelling, and functional disability that may lead to persistent joint symptoms and structural joint damage.

In our pursuit of ensuring that research aligns with the needs and interests of those most affected by gout, our team has diligently worked on the identification and consensus of the most crucial outcomes to be measured in all clinical trials and observational studies of gout.

Our work so far has incorporated key elements of the OMERACT Framework, including a thorough literature review, Delphi surveys, and patient involvement at all stages of the research process. We have developed a Core Domain Set that reflects not only the clinical aspects of gout but also the lived experience of patients.

Next Steps:
Building on the progress we've made, our next focus is to provide explicit guidance on the measurement methods and reporting needs for the core outcome set.