OMERACT strives to improve 
endpoint outcome measurement 
through a data driven, iterative consensus process involving relevant stakeholder groups.

The OMERACT Process

OMERACT strives to improve endpoint outcome measurement through a data driven, iterative consensus process involving relevant stakeholder groups. The work of OMERACT is facilitated by participants within various working groups who provide input on the development of the OMERACT research agendas. The individual research agendas focus on measurement issues considering Truth, Discrimination and Feasibility, the backbone of the OMERACT Filter. A powerful and important aspect of OMERACT is the integration of patients at each stage of the OMERACT process. This patient input along with clinical trialist insight, epidemiologist assessment, and industry perspective, has led OMERACT to be a unique decision making group in developing outcome measures for all types of clinical trials and observational research.

Truth Is the measure truthful, does it measure what it intends to measure? Is the result unbiased and relevant? This criterion captures the issues of face, content, construct and criterion validity.

Discrimination Does the measure discriminate between situations that are of interest? The situations can be states at one time (for classification or prognosis) or states at different times (to measure change). This criterion captures the issues of reliability and sensitivity to change.

Feasibility Can the measure be applied easily, given constraints of time, money, and interpretability? This criterion addresses the pragmatic reality of the use of the measure, one that may be decisive in determining a measure’s success. When OMERACT endorses a core set, it is because there is consensus amongst OMERACT participants that the evidence to supports this has been clearly demonstrated.


Spirit of OMERACT

Each one of our 8 C’s can be related to one of the three factors

  • 1.

    Consensus - Commitment

  • 2.


    Respectful across 5Ps stakeholders esp patients

  • 3.


    Truly participatory across all disciplines/sectors, international representation

  • 4.


    Evidence driven

  • 5.


    Apply critical thinking, systematic

  • 6.

    Concrete Outcomes

    e.g. OMERACT Filter; Core Sets; Methods 

  • 7.

    Continuous Learning

    Updated methods and core sets

  • 8.


    Planed succession through Fellowship Pgm