Patient-Reported Outcome

any measure of a patient’s health condition, status, or experience that is reported directly by the patient without interpretation by clinicians, researchers, or others. PROs are essential for capturing symptoms, functioning, and quality-of-life impacts that cannot be observed externally (e.g., fatigue, pain).

Abbreviation: PRO

Synonyms: Self-Reported Outcomes, Patient Self-Assessments

Example
Fatigue measured by the FACIT-Fatigue Scale

Pain intensity reported on a Visual Analogue Scale (VAS)

Physical function reported by the patient on the HAQ-DI (Health Assessment Questionnaire–Disability Index)

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