a structured document that provides a clear, comprehensive description of a specific domain or topic of interest. It outlines the domain’s background and context, key concepts and definitions, and summarizes the relevant evidence and literature. A DDR serves as the foundation for later steps in developing core outcome sets or selecting measurement instruments by ensuring a shared understanding of what the domain means.
Abbreviation: DDR
Example
Before starting instrument selection for a new OMERACT Working Group on fatigue, the group prepares a Domain Definition Report (DDR). This document defines “fatigue” within the context of rheumatology, explains its importance to patients, reviews existing definitions and frameworks, and summarizes key literature, ensuring all team members are aligned on what the domain encompasses.