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									2 different core sets or just one? - Calcium Pyrophosphate Deposition (CPPD) Core Domain Set Endorsement				            </title>
            <link>https://omeract.org/forum/cppd-cds/2-different-core-sets-or-just-one/</link>
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                        <title>Answer to: 2 different core sets or just one?</title>
                        <link>https://omeract.org/forum/cppd-cds/2-different-core-sets-or-just-one/#post-18</link>
                        <pubDate>Tue, 28 Oct 2025 13:00:55 +0000</pubDate>
                        <description><![CDATA[Thanks for this comment. The decision to develop two core sets was made very early in the development process, with a vote to take this approach at a virtual OMERACT SIG in 2020. We used thi...]]></description>
                        <content:encoded><![CDATA[<p><span>Thanks for this comment. The decision to develop two core sets was made very early in the development process, with a vote to take this approach at a virtual </span><a class="glossaryLink" role="link" href="https://omeract.org/glossary/omeract/" aria-describedby="tt" data-cmtooltip="&lt;div class=glossaryItemTitle&gt;OMERACT&lt;/div&gt;&lt;div class=glossaryItemBody&gt; OMERACT is a global, volunteer-driven, not for profit organisation committed to improving outcomes for patients with autoimmune and musculoskeletal diseases through advancing the design and quality of clinical studies.Through rigorous methodology and our global Working Groups, OMERACT supports the development of Core Outcome Sets (COS), identifying patient and disease-relevant areas to be measured (domains) and the corresponding measurement instruments for use in clinical trials, including those for regulatory approval of new treatments. &lt;/div&gt;" data-mobile-support="0" data-gt-translate-attributes="">OMERACT</a><span> SIG in 2020. We used this approach in all the </span><a class="glossaryLink" role="link" href="https://omeract.org/glossary/delphi/" aria-describedby="tt" data-cmtooltip="&lt;div class=glossaryItemTitle&gt;Delphi&lt;/div&gt;&lt;div class=glossaryItemBody&gt; a structured, anonymous, and iterative consultation method used to achieve consensus among a group of experts or stakeholders. It involves multiple rounds of questioning, feedback, and re-rating to refine opinions and move toward agreement on key issues.Synonyms: Delphi Survey, Delphi MethodExampleAn OMERACT working group uses the Delphi Method to identify which patient-reported outcomes are most important for a new core domain set. Participants anonymously rate the importance of each domain over several rounds until consensus is reached. &lt;/div&gt;" data-mobile-support="0" data-gt-translate-attributes="">Delphi</a><span> exercises. This aligns with the approach taken for the </span><a class="glossaryLink" role="link" href="https://omeract.org/glossary/omeract/" aria-describedby="tt" data-cmtooltip="&lt;div class=glossaryItemTitle&gt;OMERACT&lt;/div&gt;&lt;div class=glossaryItemBody&gt; OMERACT is a global, volunteer-driven, not for profit organisation committed to improving outcomes for patients with autoimmune and musculoskeletal diseases through advancing the design and quality of clinical studies.Through rigorous methodology and our global Working Groups, OMERACT supports the development of Core Outcome Sets (COS), identifying patient and disease-relevant areas to be measured (domains) and the corresponding measurement instruments for use in clinical trials, including those for regulatory approval of new treatments. &lt;/div&gt;" data-mobile-support="0" data-gt-translate-attributes="">OMERACT</a><span> core domains for gout, another crystal arthritis (gout flare domains and long-term gout domains). For CPPD, the core outcomes for acute CPP crystal arthritis and the core outcomes for </span><a class="glossaryLink" role="link" href="https://omeract.org/glossary/chronic/" aria-describedby="tt" data-cmtooltip="&lt;div class=glossaryItemTitle&gt;Chronic&lt;/div&gt;&lt;div class=glossaryItemBody&gt; a disease or condition that lasts for a long time—often for months, years, or a lifetime—and typically requires ongoing management rather than a one-time cure. Chronic conditions may be stable, progressive, or fluctuating, but they generally persist rather than resolve quickly.Synonyms: Long-term, LifelongExampleDiabetes mellitus is a chronic condition. It cannot currently be cured, but it can be managed with medication, diet, and lifestyle changes to maintain health over a person’s lifetime. &lt;/div&gt;" data-mobile-support="0" data-gt-translate-attributes="">chronic</a><span> and recurrent CPPD disease are not the same, although there are some overlapping domains (for example pain intensity, overall function, and </span><a class="glossaryLink" role="link" href="https://omeract.org/glossary/patient/" aria-describedby="tt" data-cmtooltip="&lt;div class=glossaryItemTitle&gt;Patient&lt;/div&gt;&lt;div class=glossaryItemBody&gt; a person who is receiving, has received, or may receive health care services. This includes individuals facing health-related decisions (such as whether to undergo screening), those being evaluated for a condition (diagnostic testing), or those undergoing treatment for an existing disease. In broader contexts, the term also encompasses people seeking preventive care or participating in health programs.Abbreviation: PtSynonyms: Health Care Consumer, Health Consumer, End User (in the context of patient decision aids)ExampleA 52-year-old woman considering whether to have a mammogram is a patient because she is making a health-related screening decision and may receive care based on the outcome of that decision. &lt;/div&gt;" data-mobile-support="0" data-gt-translate-attributes="">patient</a><span> global assessment).</span></p>]]></content:encoded>
						                            <category domain="https://omeract.org/forum/cppd-cds/">Calcium Pyrophosphate Deposition (CPPD) Core Domain Set Endorsement</category>                        <dc:creator>omeractadmin</dc:creator>
                        <guid isPermaLink="true">https://omeract.org/forum/cppd-cds/2-different-core-sets-or-just-one/#post-18</guid>
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				                    <item>
                        <title>2 different core sets or just one?</title>
                        <link>https://omeract.org/forum/cppd-cds/2-different-core-sets-or-just-one/#post-14</link>
                        <pubDate>Mon, 27 Oct 2025 12:12:20 +0000</pubDate>
                        <description><![CDATA[I think you should go ahead with what you have now, we don&#039;t want to delay things. But having arrived at this point, I note the core sets show strong overlap, so in a revision you could merg...]]></description>
                        <content:encoded><![CDATA[<p>I think you should go ahead with what you have now, we don't want to delay things. But having arrived at this point, I note the core sets show strong overlap, so in a revision you could merge them and make the differences situation-specific.</p>]]></content:encoded>
						                            <category domain="https://omeract.org/forum/cppd-cds/">Calcium Pyrophosphate Deposition (CPPD) Core Domain Set Endorsement</category>                        <dc:creator>Maarten Boers</dc:creator>
                        <guid isPermaLink="true">https://omeract.org/forum/cppd-cds/2-different-core-sets-or-just-one/#post-14</guid>
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